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Canonical and non-canonical JAK/STAT transcriptional targets may be involved in distinct and overlapping cellular processes

BACKGROUND: The Janus kinase-signal transducer and activator of transcription (JAK/STAT) pathway has been well-characterized as a crucial signal transduction cascade that regulates vital biological responses including development, immunity and oncogenesis. Additionally to its canonical pathway that...

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Detalles Bibliográficos
Autores principales: Tsurumi, Amy, Zhao, Connie, Li, Willis X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594485/
https://www.ncbi.nlm.nih.gov/pubmed/28893190
http://dx.doi.org/10.1186/s12864-017-4058-y