Imipramine blocks acute silicosis in a mouse model

BACKGROUND: Inhalation of crystalline silica is associated with pulmonary inflammation and silicosis. Although silicosis remains a prevalent health problem throughout the world, effective treatment choices are limited. Imipramine (IMP) is a FDA approved tricyclic antidepressant drug with lysosomotro...

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Detalles Bibliográficos
Autores principales: Biswas, Rupa, Trout, Kevin L., Jessop, Forrest, Harkema, Jack R., Holian, Andrij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594487/
https://www.ncbi.nlm.nih.gov/pubmed/28893276
http://dx.doi.org/10.1186/s12989-017-0217-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594487/
https://www.ncbi.nlm.nih.gov/pubmed/28893276
http://dx.doi.org/10.1186/s12989-017-0217-1

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