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Antiproliferative factor (APF) binds specifically to sites within the cytoskeleton-associated protein 4 (CKAP4) extracellular domain

BACKGROUND: Antiproliferative factor (APF) is a sialoglycopeptide elevated in the urine of patients with interstitial cystitis—a chronic, painful bladder disease. APF inhibits the proliferation of normal bladder epithelial cells and cancer cells in vitro, presumably by binding to its cellular recept...

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Detalles Bibliográficos
Autores principales: Chavda, Burzin, Ling, Jun, Majernick, Thomas, Planey, Sonia Lobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594493/
https://www.ncbi.nlm.nih.gov/pubmed/28893174
http://dx.doi.org/10.1186/s12858-017-0088-y