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Antiproliferative factor (APF) binds specifically to sites within the cytoskeleton-associated protein 4 (CKAP4) extracellular domain
BACKGROUND: Antiproliferative factor (APF) is a sialoglycopeptide elevated in the urine of patients with interstitial cystitis—a chronic, painful bladder disease. APF inhibits the proliferation of normal bladder epithelial cells and cancer cells in vitro, presumably by binding to its cellular recept...
Autores principales: | Chavda, Burzin, Ling, Jun, Majernick, Thomas, Planey, Sonia Lobo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594493/ https://www.ncbi.nlm.nih.gov/pubmed/28893174 http://dx.doi.org/10.1186/s12858-017-0088-y |
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