p53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions

BACKGROUND: As an important cellular stress sensor phosphoprotein p53 can trigger cell cycle arrest and apoptosis and regulate autophagy. The p53 activity mainly depends on its transactivating function, however, how p53 can select one or another biological outcome is still a matter of profound studi...

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Detalles Bibliográficos
Autores principales: Garufi, Alessia, Pistritto, Giuseppa, Baldari, Silvia, Toietta, Gabriele, Cirone, Mara, D’Orazi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594515/
https://www.ncbi.nlm.nih.gov/pubmed/28893313
http://dx.doi.org/10.1186/s13046-017-0596-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594515/
https://www.ncbi.nlm.nih.gov/pubmed/28893313
http://dx.doi.org/10.1186/s13046-017-0596-z

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