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Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets

BACKGROUND: Pancreatic β-cells require a constant supply of zinc to maintain normal insulin secretory function. Following co-exocytosis with insulin, zinc is replenished via the Zrt- and Irt-like (ZIP; SLC39A) family of transporters. However the ZIP paralogues of particular importance for zinc uptak...

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Detalles Bibliográficos
Autores principales: Lawson, Rebecca, Maret, Wolfgang, Hogstrand, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594519/
https://www.ncbi.nlm.nih.gov/pubmed/28893192
http://dx.doi.org/10.1186/s12864-017-4119-2