Loss of Tff1 Promotes Pro-Inflammatory Phenotype with Increase in the Levels of RORγt+ T Lymphocytes and Il-17 in Mouse Gastric Neoplasia

Background: TFF1 deficiency induces a mucosal pro-inflammatory phenotype that contributes to gastric tumorigenesis in mouse and human. Methods: We utilized the Tff1-KO mouse model to assess the impact of TFF1 loss on immune cells infiltration in the stomach. We used single cell suspension, flow cyto...

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Detalles Bibliográficos
Autores principales: Soutto, Mohammed, Saleh, Mohamed, Arredouani, Mohamed S, Piazuelo, Blanca, Belkhiri, Abbes, El-Rifai, Wael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595071/
https://www.ncbi.nlm.nih.gov/pubmed/28900479
http://dx.doi.org/10.7150/jca.19639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595071/
https://www.ncbi.nlm.nih.gov/pubmed/28900479
http://dx.doi.org/10.7150/jca.19639

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