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Platelet-Targeted Delivery of Peripheral Blood Mononuclear Cells to the Ischemic Heart Restores Cardiac Function after Ischemia-Reperfusion Injury

One of the major hurdles in intravenous regenerative cell therapy is the low homing efficiency to the area where these cells are needed. To increase cell homing toward areas of myocardial damage, we developed a bispecific tandem single-chain antibody (Tand-scFv(Sca-1+GPIIb/IIIa)) that binds with hig...

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Detalles Bibliográficos
Autores principales: Ziegler, Melanie, Wang, Xiaowei, Lim, Bock, Leitner, Ephraem, Klingberg, Franco, Ching, Victoria, Yao, Yu, Huang, Dexing, Gao, Xiao-Ming, Kiriazis, Helen, Du, Xiao-Jun, Haigh, Jody J., Bobik, Alex, Hagemeyer, Christoph E., Ahrens, Ingo, Peter, Karlheinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595126/
https://www.ncbi.nlm.nih.gov/pubmed/28900504
http://dx.doi.org/10.7150/thno.19698