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Platelet-Targeted Delivery of Peripheral Blood Mononuclear Cells to the Ischemic Heart Restores Cardiac Function after Ischemia-Reperfusion Injury
One of the major hurdles in intravenous regenerative cell therapy is the low homing efficiency to the area where these cells are needed. To increase cell homing toward areas of myocardial damage, we developed a bispecific tandem single-chain antibody (Tand-scFv(Sca-1+GPIIb/IIIa)) that binds with hig...
Autores principales: | Ziegler, Melanie, Wang, Xiaowei, Lim, Bock, Leitner, Ephraem, Klingberg, Franco, Ching, Victoria, Yao, Yu, Huang, Dexing, Gao, Xiao-Ming, Kiriazis, Helen, Du, Xiao-Jun, Haigh, Jody J., Bobik, Alex, Hagemeyer, Christoph E., Ahrens, Ingo, Peter, Karlheinz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595126/ https://www.ncbi.nlm.nih.gov/pubmed/28900504 http://dx.doi.org/10.7150/thno.19698 |
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