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Combination of AAV-TRAIL with miR-221-Zip Therapeutic Strategy Overcomes the Resistance to TRAIL Induced Apoptosis in Liver Cancer

TNF-related apoptosis-inducing ligand (TRAIL) possesses the capacity to induce apoptosis in a wide variety of tumor cells without affecting most normal cells. However, it has now emerged that many primary cancer cells are resistant to TRAIL monotherapy. Overcoming the intrinsic or acquired TRAIL res...

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Detalles Bibliográficos
Autores principales: Ma, Sisi, Sun, Jiazeng, Guo, Yabin, Zhang, Peng, Liu, Yanxin, Zheng, Dexian, Shi, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595128/
https://www.ncbi.nlm.nih.gov/pubmed/28900506
http://dx.doi.org/10.7150/thno.19893