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Amino-functionalized poloxamer 407 with both mucoadhesive and thermosensitive properties: preparation, characterization and application in a vaginal drug delivery system

Lack of mucoadhesive properties is the major drawback to poloxamer 407 (F127)-based in situ hydrogels for mucosal administration. The objective of the present study was to construct a novel mucoadhesive and thermosensitive in situ hydrogel drug delivery system based on an amino-functionalized poloxa...

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Detalles Bibliográficos
Autores principales: Ci, Liqian, Huang, Zhigang, Liu, Yu, Liu, Zhepeng, Wei, Gang, Lu, Weiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595263/
https://www.ncbi.nlm.nih.gov/pubmed/28924553
http://dx.doi.org/10.1016/j.apsb.2017.03.002