Potassium 2-(1-hydroxypentyl)-benzoate attenuates neuronal apoptosis in neuron–astrocyte co-culture system through neurotrophy and neuroinflammation pathway

Potassium 2-(1-hydroxypentyl)-benzoate (d,l-PHPB), a new drug candidate for ischemic stroke at the phase II clinic trial, has been shown to protect neurons by inhibiting oxidative injury and reducing neuron apoptosis in previous studies. But the mechanisms of d,l-PHPB remain to be studied. In this s...

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Detalles Bibliográficos
Autores principales: Liu, Dongmei, Zhang, Man, Rong, Xianfang, Li, Jiang, Wang, Xiaoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595293/
https://www.ncbi.nlm.nih.gov/pubmed/28924549
http://dx.doi.org/10.1016/j.apsb.2017.06.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595293/
https://www.ncbi.nlm.nih.gov/pubmed/28924549
http://dx.doi.org/10.1016/j.apsb.2017.06.006

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