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Engineering human cell spheroids to model embryonic tissue fusion in vitro

Epithelial-mesenchymal interactions drive embryonic fusion events during development, and perturbations of these interactions can result in birth defects. Cleft palate and neural tube defects can result from genetic defects or environmental exposures during development, yet very little is known abou...

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Detalles Bibliográficos
Autores principales: Belair, David G., Wolf, Cynthia J., Wood, Carmen, Ren, Hongzu, Grindstaff, Rachel, Padgett, William, Swank, Adam, MacMillan, Denise, Fisher, Anna, Winnik, Witold, Abbott, Barbara D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595299/
https://www.ncbi.nlm.nih.gov/pubmed/28898253
http://dx.doi.org/10.1371/journal.pone.0184155