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Iron imaging reveals tumor and metastasis macrophage hemosiderin deposits in breast cancer

Iron-deposition is a metabolic biomarker of macrophages in both normal and pathological situations, but the presence of iron in tumor and metastasis-associated macrophages is not known. Here we mapped and quantified hemosiderin-laden macrophage (HLM) deposits in murine models of metastatic breast ca...

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Detalles Bibliográficos
Autores principales: Leftin, Avigdor, Ben-Chetrit, Nir, Klemm, Florian, Joyce, Johanna A., Koutcher, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595304/
https://www.ncbi.nlm.nih.gov/pubmed/28898277
http://dx.doi.org/10.1371/journal.pone.0184765