Cyclic stretch induced IL-33 production through HMGB1/TLR-4 signaling pathway in murine respiratory epithelial cells

Interleukin 33 (IL-33), an inflammatory and mechanically responsive cytokine, is an important component of a TLR4-dependent innate immune process in mucosal epithelium. Although TLR4 also plays a role in sensing biomechanical stretch, a pathway of stretch-induced TLR4-dependent IL-33 biosynthesis ha...

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Detalles Bibliográficos
Autores principales: Chang, Jing, Xia, Yuefeng, Wasserloos, Karla, Deng, Meihong, Blose, Kory J., Vorp, David A., Turnquist, Heth R., Billiar, Timothy R., Pitt, Bruce A., Zhang, Ma-Zhong, Zhang, Li-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595336/
https://www.ncbi.nlm.nih.gov/pubmed/28898270
http://dx.doi.org/10.1371/journal.pone.0184770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595336/
https://www.ncbi.nlm.nih.gov/pubmed/28898270
http://dx.doi.org/10.1371/journal.pone.0184770

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