Sigma 1 receptor regulates ERK activation and promotes survival of optic nerve head astrocytes

The sigma 1 receptor (S1R) is a unique transmembrane protein that has been shown to regulate neuronal differentiation and cellular survival. It is expressed within several cell types throughout the nervous system and visceral organs, including neurons and glia within the eye. S1R ligands are therape...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Mysona, Barbara A., Wang, Jing, Gonsalvez, Graydon B., Smith, Sylvia B., Bollinger, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595338/
https://www.ncbi.nlm.nih.gov/pubmed/28898265
http://dx.doi.org/10.1371/journal.pone.0184421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595338/
https://www.ncbi.nlm.nih.gov/pubmed/28898265
http://dx.doi.org/10.1371/journal.pone.0184421

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