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Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage

Kaposi’s sarcoma (KS)-associated herpesvirus (KSHV) is a human gammaherpesvirus recognized as the principal causative agent of KS and primary effusion lymphoma (PEL). KSHV establishes persistent latent infection in B lymphocytes where viral gene expression is restricted, in part, by a cohesin-depend...

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Detalles Bibliográficos
Autores principales: De Leo, Alessandra, Chen, Horng-Shen, Hu, Chih-Chi Andrew, Lieberman, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595345/
https://www.ncbi.nlm.nih.gov/pubmed/28854249
http://dx.doi.org/10.1371/journal.ppat.1006596