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Autophagy promotes degradation of polyethyleneimine–alginate nanoparticles in endothelial progenitor cells

Polyethyleneimine (PEI)–alginate (Alg) nanoparticle (NP) is a safe and effective vector for delivery of siRNA or DNA. Recent studies suggest that autophagy is related to cytotoxicity of PEI NPs. However, contribution of autophagy to degradation of PEI–Alg NPs remains unknown. CD34(+)VEGFR-3(+) endot...

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Detalles Bibliográficos
Autores principales: Wang, Guo-dong, Tan, Yu-zhen, Wang, Hai-jie, Zhou, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595362/
https://www.ncbi.nlm.nih.gov/pubmed/28924349
http://dx.doi.org/10.2147/IJN.S141592