Genome-wide analysis of parent-of-origin interaction effects with environmental exposure (PoOxE): An application to European and Asian cleft palate trios

Cleft palate only is a common birth defect with high heritability. Only a small fraction of this heritability is explained by the genetic variants identified so far, underscoring the need to investigate other disease mechanisms, such as gene-environment (GxE) interactions and parent-of-origin (PoO)...

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Detalles Bibliográficos
Autores principales: Haaland, Øystein A., Jugessur, Astanand, Gjerdevik, Miriam, Romanowska, Julia, Shi, Min, Beaty, Terri H., Marazita, Mary L., Murray, Jeffrey C., Wilcox, Allen J., Lie, Rolv T., Gjessing, Håkon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595425/
https://www.ncbi.nlm.nih.gov/pubmed/28898263
http://dx.doi.org/10.1371/journal.pone.0184358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595425/
https://www.ncbi.nlm.nih.gov/pubmed/28898263
http://dx.doi.org/10.1371/journal.pone.0184358

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