FXR1 regulates transcription and is required for growth of human cancer cells with TP53/FXR2 homozygous deletion

Tumor suppressor p53 prevents cell transformation by inducing apoptosis and other responses. Homozygous TP53 deletion occurs in various types of human cancers for which no therapeutic strategies have yet been reported. TCGA database analysis shows that the TP53 homozygous deletion locus mostly exhib...

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Detalles Bibliográficos
Autores principales: Fan, Yichao, Yue, Jiao, Xiao, Mengtao, Han-Zhang, Han, Wang, Yao Vickie, Ma, Chun, Deng, Zhilin, Li, Yingxiang, Yu, Yanyan, Wang, Xinghao, Niu, Shen, Hua, Youjia, Weng, Zhiping, Atadja, Peter, Li, En, Xiang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595435/
https://www.ncbi.nlm.nih.gov/pubmed/28767039
http://dx.doi.org/10.7554/eLife.26129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595435/
https://www.ncbi.nlm.nih.gov/pubmed/28767039
http://dx.doi.org/10.7554/eLife.26129

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