A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia

The genetic mechanisms regulating the brain and behaviour across the lifespan are poorly understood. We found that lifespan transcriptome trajectories describe a calendar of gene regulatory events in the brain of humans and mice. Transcriptome trajectories defined a sequence of gene expression chang...

Descripción completa

Detalles Bibliográficos
Autores principales: Skene, Nathan G, Roy, Marcia, Grant, Seth GN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595438/
https://www.ncbi.nlm.nih.gov/pubmed/28893375
http://dx.doi.org/10.7554/eLife.17915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595438/
https://www.ncbi.nlm.nih.gov/pubmed/28893375
http://dx.doi.org/10.7554/eLife.17915

Ejemplares similares