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A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia
The genetic mechanisms regulating the brain and behaviour across the lifespan are poorly understood. We found that lifespan transcriptome trajectories describe a calendar of gene regulatory events in the brain of humans and mice. Transcriptome trajectories defined a sequence of gene expression chang...
Autores principales: | Skene, Nathan G, Roy, Marcia, Grant, Seth GN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595438/ https://www.ncbi.nlm.nih.gov/pubmed/28893375 http://dx.doi.org/10.7554/eLife.17915 |
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