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Analysis of individual cells identifies cell‐to‐cell variability following induction of cellular senescence

Senescent cells play important roles in both physiological and pathological processes, including cancer and aging. In all cases, however, senescent cells comprise only a small fraction of tissues. Senescent phenotypes have been studied largely in relatively homogeneous populations of cultured cells....

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Detalles Bibliográficos
Autores principales: Wiley, Christopher D., Flynn, James M., Morrissey, Christapher, Lebofsky, Ronald, Shuga, Joe, Dong, Xiao, Unger, Marc A., Vijg, Jan, Melov, Simon, Campisi, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595671/
https://www.ncbi.nlm.nih.gov/pubmed/28699239
http://dx.doi.org/10.1111/acel.12632