Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers

Reduced neurogenesis in the aging mammalian hippocampus has been linked to cognitive deficits and increased risk of dementia. We utilized postmortem human hippocampal tissue from 26 subjects aged 18–88 years to investigate changes in expression of six genes representing different stages of neurogene...

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Detalles Bibliográficos
Autores principales: Mathews, Kathryn J., Allen, Katherine M., Boerrigter, Danny, Ball, Helen, Shannon Weickert, Cynthia, Double, Kay L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Short Takes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595679/
https://www.ncbi.nlm.nih.gov/pubmed/28766905
http://dx.doi.org/10.1111/acel.12641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595679/
https://www.ncbi.nlm.nih.gov/pubmed/28766905
http://dx.doi.org/10.1111/acel.12641

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