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In vivo imaging reveals mitophagy independence in the maintenance of axonal mitochondria during normal aging

Mitophagy is thought to be a critical mitochondrial quality control mechanism in neurons and has been extensively studied in neurological disorders such as Parkinson's disease. However, little is known about how mitochondria are maintained in the lengthy neuronal axons in the context of physiol...

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Detalles Bibliográficos
Autores principales: Cao, Xu, Wang, Haiqiong, Wang, Zhao, Wang, Qingyao, Zhang, Shuang, Deng, Yuanping, Fang, Yanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595681/
https://www.ncbi.nlm.nih.gov/pubmed/28782874
http://dx.doi.org/10.1111/acel.12654