Serpine 1 induces alveolar type II cell senescence through activating p53‐p21‐Rb pathway in fibrotic lung disease

Senescence of alveolar type 2 (ATII) cells, progenitors of the alveolar epithelium, is implicated in the pathogeneses of idiopathic pulmonary fibrosis (IPF), an aging‐related progressive fatal lung disorder with unknown etiology. The mechanism underlying ATII cell senescence in fibrotic lung disease...

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Detalles Bibliográficos
Autores principales: Jiang, Chunsun, Liu, Gang, Luckhardt, Tracy, Antony, Veena, Zhou, Yong, Carter, A. Brent, Thannickal, Victor J., Liu, Rui‐Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595683/
https://www.ncbi.nlm.nih.gov/pubmed/28722352
http://dx.doi.org/10.1111/acel.12643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595683/
https://www.ncbi.nlm.nih.gov/pubmed/28722352
http://dx.doi.org/10.1111/acel.12643

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