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FOXO3 longevity interactome on chromosome 6

FOXO3 has been implicated in longevity in multiple populations. By DNA sequencing in long‐lived individuals, we identified all single nucleotide polymorphisms (SNPs) in FOXO3 and showed 41 were associated with longevity. Thirteen of these had predicted alterations in transcription factor binding sit...

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Detalles Bibliográficos
Autores principales: Donlon, Timothy A., Morris, Brian J., Chen, Randi, Masaki, Kamal H., Allsopp, Richard C., Willcox, D. Craig, Elliott, Ayako, Willcox, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595686/
https://www.ncbi.nlm.nih.gov/pubmed/28722347
http://dx.doi.org/10.1111/acel.12625