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Translation fidelity coevolves with longevity

Whether errors in protein synthesis play a role in aging has been a subject of intense debate. It has been suggested that rare mistakes in protein synthesis in young organisms may result in errors in the protein synthesis machinery, eventually leading to an increasing cascade of errors as organisms...

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Detalles Bibliográficos
Autores principales: Ke, Zhonghe, Mallik, Pramit, Johnson, Adam B., Luna, Facundo, Nevo, Eviatar, Zhang, Zhengdong D., Gladyshev, Vadim N., Seluanov, Andrei, Gorbunova, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595694/
https://www.ncbi.nlm.nih.gov/pubmed/28707419
http://dx.doi.org/10.1111/acel.12628