Cargando…

Cooperation between p21 and Akt is required for p53‐dependent cellular senescence

Cellular senescence has been implicated in normal aging, tissue homeostasis, and tumor suppression. Although p53 has been shown to be a central mediator of cellular senescence, the signaling pathway by which it induces senescence remains incompletely understood. In this study, we have shown that bot...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Young Yeon, Jee, Hye Jin, Um, Jee‐Hyun, Kim, Young Mi, Bae, Sun Sik, Yun, Jeanho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595696/
https://www.ncbi.nlm.nih.gov/pubmed/28691365
http://dx.doi.org/10.1111/acel.12639