Epigenetic regulation by G9a/GLP complex ameliorates amyloid‐beta 1‐42 induced deficits in long‐term plasticity and synaptic tagging/capture in hippocampal pyramidal neurons

Altered epigenetic mechanisms are implicated in the cognitive decline associated with neurodegenerative diseases such as in Alzheimer's disease (AD). AD is the most prevalent form of dementia worldwide; amyloid plaques and neurofibrillary tangles are the histopathological hallmarks of AD. We ha...

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Detalles Bibliográficos
Autores principales: Sharma, Mahima, Dierkes, Tobias, Sajikumar, Sreedharan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595698/
https://www.ncbi.nlm.nih.gov/pubmed/28665013
http://dx.doi.org/10.1111/acel.12634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595698/
https://www.ncbi.nlm.nih.gov/pubmed/28665013
http://dx.doi.org/10.1111/acel.12634

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