Methylation of the ribosomal RNA gene promoter is associated with aging and age‐related decline

The transcription of ribosomal RNA genes (rDNA) is subject to epigenetic regulation, as it is abrogated by the methylation of CpG dinucleotides within their promoter region. Here, we investigated, through Sequenom platform, the age‐related methylation status of the CpG island falling into the rDNA p...

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Detalles Bibliográficos
Autores principales: D'Aquila, Patrizia, Montesanto, Alberto, Mandalà, Maurizio, Garasto, Sabrina, Mari, Vincenzo, Corsonello, Andrea, Bellizzi, Dina, Passarino, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595699/
https://www.ncbi.nlm.nih.gov/pubmed/28625020
http://dx.doi.org/10.1111/acel.12603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595699/
https://www.ncbi.nlm.nih.gov/pubmed/28625020
http://dx.doi.org/10.1111/acel.12603

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