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Small RNAs induce the activation of the pro‐inflammatory TLR7 signaling pathway in aged rat kidney

We have recently reported that TLR‐related genes, including TLR7, are upregulated during aging. However, the role of TLR7 and its endogenous ligand in inflammation related to aging is not well defined. Here, we established that small RNAs trigger age‐related renal inflammation via TLR7 signaling pat...

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Detalles Bibliográficos
Autores principales: Lee, Eun Kyeong, Chung, Ki Wung, Kim, Ye Ra, Ha, Sugyeong, Kim, Sung Dae, Kim, Dae Hyun, Jung, Kyung Jin, Lee, Bonggi, Im, Eunok, Yu, Byung Pal, Chung, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595700/
https://www.ncbi.nlm.nih.gov/pubmed/28665028
http://dx.doi.org/10.1111/acel.12629