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Enhanced transport of plant‐produced rabies single‐chain antibody‐RVG peptide fusion protein across an in cellulo blood–brain barrier device

The biomedical applications of antibody engineering are developing rapidly and have been expanded to plant expression platforms. In this study, we have generated a novel antibody molecule in planta for targeted delivery across the blood–brain barrier (BBB). Rabies virus (RABV) is a neurotropic virus...

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Detalles Bibliográficos
Autores principales: Phoolcharoen, Waranyoo, Prehaud, Christophe, van Dolleweerd, Craig J., Both, Leonard, da Costa, Anaelle, Lafon, Monique, Ma, Julian K‐C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595719/
https://www.ncbi.nlm.nih.gov/pubmed/28273388
http://dx.doi.org/10.1111/pbi.12719