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Enhanced transport of plant‐produced rabies single‐chain antibody‐RVG peptide fusion protein across an in cellulo blood–brain barrier device
The biomedical applications of antibody engineering are developing rapidly and have been expanded to plant expression platforms. In this study, we have generated a novel antibody molecule in planta for targeted delivery across the blood–brain barrier (BBB). Rabies virus (RABV) is a neurotropic virus...
Autores principales: | Phoolcharoen, Waranyoo, Prehaud, Christophe, van Dolleweerd, Craig J., Both, Leonard, da Costa, Anaelle, Lafon, Monique, Ma, Julian K‐C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595719/ https://www.ncbi.nlm.nih.gov/pubmed/28273388 http://dx.doi.org/10.1111/pbi.12719 |
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