Adolescent THC Exposure Causes Enduring Prefrontal Cortical Disruption of GABAergic Inhibition and Dysregulation of Sub-Cortical Dopamine Function

Chronic adolescent marijuana use has been linked to the later development of psychiatric diseases such as schizophrenia. GABAergic hypofunction in the prefrontal cortex (PFC) is a cardinal pathological feature of schizophrenia and may be a mechanism by which the PFC loses its ability to regulate sub...

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Detalles Bibliográficos
Autores principales: Renard, Justine, Szkudlarek, Hanna J., Kramar, Cecilia P., Jobson, Christina E. L., Moura, Kyra, Rushlow, Walter J., Laviolette, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595795/
https://www.ncbi.nlm.nih.gov/pubmed/28900286
http://dx.doi.org/10.1038/s41598-017-11645-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595795/
https://www.ncbi.nlm.nih.gov/pubmed/28900286
http://dx.doi.org/10.1038/s41598-017-11645-8

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