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Adolescent THC Exposure Causes Enduring Prefrontal Cortical Disruption of GABAergic Inhibition and Dysregulation of Sub-Cortical Dopamine Function
Chronic adolescent marijuana use has been linked to the later development of psychiatric diseases such as schizophrenia. GABAergic hypofunction in the prefrontal cortex (PFC) is a cardinal pathological feature of schizophrenia and may be a mechanism by which the PFC loses its ability to regulate sub...
Autores principales: | Renard, Justine, Szkudlarek, Hanna J., Kramar, Cecilia P., Jobson, Christina E. L., Moura, Kyra, Rushlow, Walter J., Laviolette, Steven R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595795/ https://www.ncbi.nlm.nih.gov/pubmed/28900286 http://dx.doi.org/10.1038/s41598-017-11645-8 |
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