Identification of key metabolic changes during liver fibrosis progression in rats using a urine and serum metabolomics approach

Reversibility of hepatic fibrosis is an intrinsic response to chronic injury, and with on-going damage, fibrosis can progress to its end-stage consequence, cirrhosis. Non-invasive and reliable biomarkers for early detection of liver fibrosis are needed. Based on the CCl(4)-induced liver fibrosis rat...

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Detalles Bibliográficos
Autores principales: Chang, Hong, Meng, Hong-yu, Liu, Shu-min, Wang, Yu, Yang, Xiao-xu, Lu, Fang, Wang, Hong-yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595818/
https://www.ncbi.nlm.nih.gov/pubmed/28900168
http://dx.doi.org/10.1038/s41598-017-11759-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595818/
https://www.ncbi.nlm.nih.gov/pubmed/28900168
http://dx.doi.org/10.1038/s41598-017-11759-z

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