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Identification of key metabolic changes during liver fibrosis progression in rats using a urine and serum metabolomics approach
Reversibility of hepatic fibrosis is an intrinsic response to chronic injury, and with on-going damage, fibrosis can progress to its end-stage consequence, cirrhosis. Non-invasive and reliable biomarkers for early detection of liver fibrosis are needed. Based on the CCl(4)-induced liver fibrosis rat...
Autores principales: | Chang, Hong, Meng, Hong-yu, Liu, Shu-min, Wang, Yu, Yang, Xiao-xu, Lu, Fang, Wang, Hong-yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595818/ https://www.ncbi.nlm.nih.gov/pubmed/28900168 http://dx.doi.org/10.1038/s41598-017-11759-z |
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