Dynamic and Kinetic Elements of µ-Opioid Receptor Functional Selectivity

While the therapeutic effect of opioids analgesics is mainly attributed to µ-opioid receptor (MOR) activation leading to G protein signaling, their side effects have mostly been linked to β-arrestin signaling. To shed light on the dynamic and kinetic elements underlying MOR functional selectivity, w...

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Detalles Bibliográficos
Autores principales: Kapoor, Abhijeet, Martinez-Rosell, Gerard, Provasi, Davide, de Fabritiis, Gianni, Filizola, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595830/
https://www.ncbi.nlm.nih.gov/pubmed/28900175
http://dx.doi.org/10.1038/s41598-017-11483-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595830/
https://www.ncbi.nlm.nih.gov/pubmed/28900175
http://dx.doi.org/10.1038/s41598-017-11483-8

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