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Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterols

Using LC/qTOF-MS we detected lumisterol, 20-hydroxylumisterol, 22-hydroxylumisterol, 24-hydroxylumisterol, 20,22-dihydroxylumisterol, pregnalumisterol, 17-hydroxypregnalumisterol and 17,20-dihydroxypregnalumisterol in human serum and epidermis, and the porcine adrenal gland. The hydroxylumisterols i...

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Detalles Bibliográficos
Autores principales: Slominski, Andrzej T., Kim, Tae-Kang, Hobrath, Judith V., Janjetovic, Zorica, Oak, Allen S. W., Postlethwaite, Arnold, Lin, Zongtao, Li, Wei, Takeda, Yukimasa, Jetten, Anton M., Tuckey, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595834/
https://www.ncbi.nlm.nih.gov/pubmed/28900196
http://dx.doi.org/10.1038/s41598-017-10202-7