Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin α isoforms

The influenza A virus nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs from all strains of influenza A viruses contain two nuclear localization signals (NLSs): a well-studied m...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Sankhala, Rajeshwer S., Florio, Tyler J., Zhou, Lixin, Nguyen, Nhan L. T., Lokareddy, Ravi K., Cingolani, Gino, Panté, Nelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595889/
https://www.ncbi.nlm.nih.gov/pubmed/28900157
http://dx.doi.org/10.1038/s41598-017-11018-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595889/
https://www.ncbi.nlm.nih.gov/pubmed/28900157
http://dx.doi.org/10.1038/s41598-017-11018-1

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