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Adaptation of influenza A (H7N9) virus in primary human airway epithelial cells

Influenza A (H7N9) is an emerging zoonotic pathogen with pandemic potential. To understand its adaptation capability, we examined the genetic changes and cellular responses following serial infections of A (H7N9) in primary human airway epithelial cells (hAECs). After 35 serial passages, six amino a...

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Detalles Bibliográficos
Autores principales: Huang, Daniel Tsung-Ning, Lu, Chun-Yi, Chi, Ya-Hui, Li, Wan-Ling, Chang, Luan-Yin, Lai, Mei-Ju, Chen, Jin-Shing, Hsu, Wen-Ming, Huang, Li-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595892/
https://www.ncbi.nlm.nih.gov/pubmed/28900138
http://dx.doi.org/10.1038/s41598-017-10749-5