Cargando…

Rogdi Defines GABAergic Control of a Wake-promoting Dopaminergic Pathway to Sustain Sleep in Drosophila

Kohlschutter-Tönz syndrome (KTS) is a rare genetic disorder with neurological dysfunctions including seizure and intellectual impairment. Mutations at the Rogdi locus have been linked to development of KTS, yet the underlying mechanisms remain elusive. Here we demonstrate that a Drosophila homolog o...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Minjong, Jang, Donghoon, Yoo, Eunseok, Oh, Yangkyun, Sonn, Jun Young, Lee, Jongbin, Ki, Yoonhee, Son, Hyo Jin, Hwang, Onyou, Lee, Changwook, Lim, Chunghun, Choe, Joonho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595912/
https://www.ncbi.nlm.nih.gov/pubmed/28900300
http://dx.doi.org/10.1038/s41598-017-11941-3