Cargando…
Rogdi Defines GABAergic Control of a Wake-promoting Dopaminergic Pathway to Sustain Sleep in Drosophila
Kohlschutter-Tönz syndrome (KTS) is a rare genetic disorder with neurological dysfunctions including seizure and intellectual impairment. Mutations at the Rogdi locus have been linked to development of KTS, yet the underlying mechanisms remain elusive. Here we demonstrate that a Drosophila homolog o...
Autores principales: | Kim, Minjong, Jang, Donghoon, Yoo, Eunseok, Oh, Yangkyun, Sonn, Jun Young, Lee, Jongbin, Ki, Yoonhee, Son, Hyo Jin, Hwang, Onyou, Lee, Changwook, Lim, Chunghun, Choe, Joonho |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595912/ https://www.ncbi.nlm.nih.gov/pubmed/28900300 http://dx.doi.org/10.1038/s41598-017-11941-3 |
Ejemplares similares
-
The crystal structure of human Rogdi provides insight into the causes of Kohlschutter-Tönz Syndrome
por: Lee, Hakbong, et al.
Publicado: (2017) -
Histamine-HisCl1 Receptor Axis Regulates Wake-Promoting Signals in Drosophila melanogaster
por: Oh, Yangkyun, et al.
Publicado: (2013) -
SIFamide and SIFamide Receptor Define a Novel Neuropeptide Signaling to Promote Sleep in Drosophila
por: Park, Sangjin, et al.
Publicado: (2014) -
Drosophila CrebB is a Substrate of the Nonsense-Mediated mRNA Decay Pathway that Sustains Circadian Behaviors
por: Ri, Hwajung, et al.
Publicado: (2019) -
Serine metabolism in the brain regulates starvation-induced sleep suppression in Drosophila melanogaster
por: Sonn, Jun Young, et al.
Publicado: (2018)