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Metoprolol‐pridopidine drug–drug interaction and food effect assessments of pridopidine, a new drug for treatment of Huntington's disease

AIMS: Pridopidine is an oral drug in clinical development for treatment of patients with Huntington's disease. This study examined the interactions of pridopidine with in vitro cytochrome P450 activity and characterized the effects of pridopidine on CYP2D6 activity in healthy volunteers using m...

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Detalles Bibliográficos
Autores principales: Rabinovich‐Guilatt, Laura, Steiner, Lilach, Hallak, Hussein, Pastino, Gina, Muglia, Pierandrea, Spiegelstein, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595947/
https://www.ncbi.nlm.nih.gov/pubmed/28449367
http://dx.doi.org/10.1111/bcp.13317