IL-4 enhances IL-10 production in Th1 cells: implications for Th1 and Th2 regulation

IL-10 is an immunomodulatory cytokine with a critical role in limiting inflammation in immune-mediated pathologies. The mechanisms leading to IL-10 expression by CD4(+) T cells are being elucidated, with several cytokines implicated. We explored the effect of IL-4 on the natural phenomenon of IL-10...

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Detalles Bibliográficos
Autores principales: Mitchell, Ruth E., Hassan, Masriana, Burton, Bronwen R., Britton, Graham, Hill, Elaine V., Verhagen, Johan, Wraith, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595963/
https://www.ncbi.nlm.nih.gov/pubmed/28900244
http://dx.doi.org/10.1038/s41598-017-11803-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595963/
https://www.ncbi.nlm.nih.gov/pubmed/28900244
http://dx.doi.org/10.1038/s41598-017-11803-y

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