A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model

Controversially, histone deacetylase inhibitors (HDACi) are in clinical trial for the treatment of inherited retinal degeneration. Utilizing the zebrafish dye (ucd6) model, we determined if treatment with HDACi can rescue cone photoreceptor-mediated visual function. dye exhibit defective visual beha...

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Detalles Bibliográficos
Autores principales: Daly, Conor, Shine, Lisa, Heffernan, Theresa, Deeti, Sudhakar, Reynolds, Alison L., O’Connor, John J., Dillon, Eugène T., Duffy, David J., Kolch, Walter, Cagney, Gerard, Kennedy, Breandán N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595969/
https://www.ncbi.nlm.nih.gov/pubmed/28900183
http://dx.doi.org/10.1038/s41598-017-11513-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595969/
https://www.ncbi.nlm.nih.gov/pubmed/28900183
http://dx.doi.org/10.1038/s41598-017-11513-5

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