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Characterization of influenza A viruses with polymorphism in PB2 residues 701 and 702

The 701 and 702 positions of influenza PB2 polymerase subunit are previously shown to have roles on host range. Limited polymorphisms at these two residues are identified in natural isolates, thereby limiting the study of their role in the polymerase. In this study, we generated 31 viable viruses by...

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Detalles Bibliográficos
Autores principales: Chin, Alex W. H., Leong, Nathaniel K. C., Nicholls, John M., Poon, Leo L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595998/
https://www.ncbi.nlm.nih.gov/pubmed/28900145
http://dx.doi.org/10.1038/s41598-017-11625-y