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Functional dissection of hematopoietic stem cell populations with a stemness-monitoring system based on NS-GFP transgene expression

Hematopoietic stem cells (HSCs) in a steady state can be efficiently purified by selecting for a combination of several cell surface markers; however, such markers do not consistently reflect HSC activity. In this study, we successfully enriched HSCs with a unique stemness-monitoring system using a...

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Detalles Bibliográficos
Autores principales: Ali, Mohamed A. E., Fuse, Kyoko, Tadokoro, Yuko, Hoshii, Takayuki, Ueno, Masaya, Kobayashi, Masahiko, Nomura, Naho, Vu, Ha Thi, Peng, Hui, Hegazy, Ahmed M., Masuko, Masayoshi, Sone, Hirohito, Arai, Fumio, Tajima, Atsushi, Hirao, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596002/
https://www.ncbi.nlm.nih.gov/pubmed/28900302
http://dx.doi.org/10.1038/s41598-017-11909-3