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MiR-503 modulates epithelial-mesenchymal transition in silica-induced pulmonary fibrosis by targeting PI3K p85 and is sponged by lncRNA MALAT1

Silicosis is a kind of chronic, progressive and incurable lung fibrotic diseases with largely unknown and complex pathogenesis and molecular mechanisms. Mounting evidence suggests that microRNAs (miRNAs, miRs) are involved in the pathogenesis of silicosis. Our previous study based on miRNA microarra...

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Detalles Bibliográficos
Autores principales: Yan, Weiwen, Wu, Qiuyun, Yao, Wenxi, Li, Yan, Liu, Yi, Yuan, Jiali, Han, Ruhui, Yang, Jingjin, Ji, Xiaoming, Ni, Chunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596016/
https://www.ncbi.nlm.nih.gov/pubmed/28900284
http://dx.doi.org/10.1038/s41598-017-11904-8